Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB)

The aim of this solicitation is to create an innovative chemistry center to design, synthesize and deliver rationally designed compound libraries to the scientific community for use in antibacterial drug discovery programs. This center will fit within the broader aims put forth in the National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB) by synthesizing and delivering new compounds that enable an understanding of a SAR for optimal activity against Gram-negative bacterial pathogens and that provide the basis for a robust antibacterial development pipeline.